| ncRNA name | Rap1A shRNA |
| ncRNA Category | shRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RPE cell line ARPE-19 |
| Methods | shRNA knockdown, calcium switch assay, barrier function assay, CEC transmigration assay |
| Expression pattern | associated |
| Functional description | In vitro, Rap1A shRNA reduced steady-state barrier integrity, whereas Rap1B shRNA affected dynamic junctional responses. |
| PubMed ID | 24039860 |
| Year | 2013 |
| Title | Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo. |
| Drug-related ncRNA | NA |
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